Epitalon
Synthetic tetrapeptide sometimes discussed in aging and longevity circles based on limited and region-specific research.
This page is for general educational and informational purposes only. It is not medical advice and does not replace professional medical judgment. Always consult a qualified clinician before starting, stopping, or changing any medication or protocol.
Overview
Epitalon is a synthetic tetrapeptide that has been promoted in some aging and longevity discussions based on limited and region-specific research.
It is not widely recognized as a standard therapy in major guidelines.
Mechanism of action
Proposed mechanisms for epitalon include modulation of melatonin synthesis, antioxidant pathways, and gene expression related to cellular aging.
Much of this work is preclinical and remains hypothesis-generating rather than definitive.
Indications and use context
Epitalon is encountered mainly in experimental or wellness contexts and is not a standard part of evidence-based care for aging or age-related conditions.
Safety and side effects
Safety data for epitalon are limited, especially for long-term use.
Reported adverse effects have generally been mild in small series, but the absence of large, long-duration studies limits firm conclusions about safety.
Pharmacology and dosing considerations
Epitalon (Epithalon) administration follows protocols developed by the St. Petersburg Institute of Bioregulation and Gerontology.
Route: Intramuscular (IM) or Subcutaneous (SubQ).
Protocol structure and dosage:- Khavinson Protocol (Standard): 10 mg daily (IM/SubQ) for 10 consecutive days. Repeated every 6–12 months.
- Alternative (Low Dose): 100 mcg to 1 mg daily for longer durations.
This information summarizes protocols from the original Russian research.
Formulations and combinations
Epitalon often appears as a lyophilized powder for reconstitution and may be grouped conceptually with other peptides mentioned in longevity circles.
Research and evidence snapshot
The published epitalon literature includes small, heterogeneous studies, some of which focus on surrogate markers rather than hard clinical outcomes.
Frequently asked questions
Future FAQs may explore how epitalon compares with lifestyle and established medical approaches to healthy aging, and what kinds of data would be needed for broader acceptance. Answers will remain educational and non-prescriptive.
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